Sexual Health Express | Quick Confidential STI Screen | Epicentre
Sexual health · Express blood screen

A quick, confidential STI screen from one blood draw

A fast STI overview from a single blood sample, covering HIV, syphilis, hepatitis B, herpes (HSV-2) and a chlamydia antibody test. A blood-based screen, done in private. No fasting needed.

No doctor's referral 5 tests Confidential Results in 2 to 5 days
Express STI screen · 5 tests
R1,076
A quick, confidential blood-based STI screen. Payflex available, about R269 a month over four payments.
5tests
Blooddraw
2 to 5day results
Book a visit Ask on WhatsApp

No doctor's referral, no fasting. Private and confidential.

Medically reviewed by Dr Samantha Naidoo, MB ChB, FCP (SA), Medical Director. Reviewed 2 June 2026.
Quick and flexible

How would you like to get tested?

Walk in

No appointment needed. Come through any branch, Monday to Friday, 08:30 to 16:00.

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Ask first

Not sure which tests you need? Message us on WhatsApp and we will help you decide.

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4.7
Google rating
25 yrs
Open since 2001
100k+
Tests done
SANAS
Accredited labs
What's tested

What does the screen check for?

A quick, confidential STI overview from a single blood sample, covering five common infections with antibody and screening blood tests.

A blood antibody screen: this is a serology-based screen from one blood draw, not a swab or urine test. It is a fast, private overview. For a current, active infection, especially chlamydia, a urine or swab PCR screen is more reliable. HIV testing and STI care are also available free at public clinics across South Africa.

HIV

HIV Screen (ELISA). A blood test that looks for signs of HIV. A reactive result is always confirmed with a second, different test before it is treated as a diagnosis.

Syphilis

Syphilis (RPR/VDRL). A screening blood test for syphilis. A reactive result is confirmed with a further test and is very treatable.

Hepatitis B

Hepatitis B. A blood test that screens for hepatitis B, a virus that affects the liver.

Herpes (HSV-2)

Herpes Simplex Virus 2. A blood antibody test for HSV-2. It shows exposure, not where or when, so positives are discussed with a doctor.

Chlamydia (antibody)

Chlamydia IgM. A blood antibody test for chlamydia. For a current infection, a urine or swab PCR test is more reliable, so this is a screening overview.

How it works

Three steps, no GP needed

1

Book a slot or walk in

Reserve a time at your branch, or walk straight in. No doctor's referral, and no fasting needed.

2

Quick, private blood draw

A nurse takes a small blood sample in private, just a few minutes.

3

Confidential results in 2 to 5 days

A clear, confidential report within 2 to 5 working days, with a free certificate you can share with your doctor.

When this helps

Who is this for?

For anyone who wants a quick, confidential STI overview from a single blood draw.

A quick check

You want a fast STI overview from one blood draw.

Possible exposure

Unprotected sex or a new partner, and you want to check.

A new relationship

You and a partner want to test together.

Routine peace of mind

You test regularly as part of looking after your sexual health.

Prefer a blood test

You would rather give blood than a swab or urine sample for an initial screen.

Travellers and newcomers

Visiting or new to South Africa and want a private screen.

From our patients

What people say

★★★★★ 4.7 / 5 based on verified Google reviews
★★★★★

Friendly and competent staff. Both at reception and the nurse. A much simpler process than going through doctors. Thank you ladies.

A
Agata G.
Parktown North · 3 months ago
★★★★★

The staff at reception as well as the nurses are friendly and professional. I've also always received results timeously. I would give 10 stars if I could.

A
Abedah M.
Parktown North · Local Guide · 3 weeks ago
★★★★★

Highly highly highly recommend. The experience was painless and the practice was inviting and well kept. The report was extremely detailed and informative and I would have this as top of my list for preventive care.

N
Nadia P.
Observatory · 8 months ago
★★★★★

Amazing experience, highly professional staff. Very reasonable prices. Highly recommend.

C
Caitlin C.
Observatory · 1 year ago
★★★★★

I cannot recommend Juliette and her team enough, friendly and kind from the get go. Bloods were drawn with minimal discomfort and the labs came back quickly.

L
Laura S.
Hillcrest · 1 month ago
★★★★★

Excellent experience at Epicentre. The staff were professional, kind, and took time to explain everything clearly. The facility was clean, booking was easy, and I did not feel rushed.

A
Aaron R.
Hillcrest · 1 month ago

What this does not do

This is a quick, blood-based screen. It is a useful overview, but timing and the type of test matter, and serious recent exposures need urgent care.

  • Antibody (serology) blood tests have a window period: a recent infection can be missed soon after exposure, so a repeat test may be advised.
  • A reactive HIV or syphilis screen is always confirmed with a second, different test before it is treated as a diagnosis.
  • This blood screen is not the same as a PCR swab or urine test. For a current, active infection, especially chlamydia, a swab or urine PCR screen is more reliable; ask about the Small or Medium Sexual Health screens.
  • It does not cover every STI. If you may have been exposed to HIV in the last 72 hours, seek care urgently, as preventive treatment can only be started in a short window.
Common questions

Quick answers

Syphilis (RPR/VDRL), Chlamydia IgM, an HIV Screen (ELISA), Hepatitis B and Herpes Simplex Virus 2 (HSV-2). The screen is R1,076, with a confidential result in 2 to 5 working days.
It is a blood test. This is an antibody and screening blood panel from one draw, which is why it is quick. For a current infection, especially chlamydia, a urine or swab PCR screen is more reliable.
Yes. Your visit and result are private, with a result certificate you can choose to share with a doctor or a partner.
Antibody tests can miss a very recent infection, so if your exposure was recent a repeat test may be advised. If you may have been exposed to HIV in the last 72 hours, seek care urgently.
No doctor's referral and no fasting. Book or walk in to any branch in Cape Town, Durban or Johannesburg.
At our three walk-in labs: Observatory in Cape Town, Hillcrest in Durban and Parktown North in Johannesburg, Monday to Friday, 08:30 to 16:00.
Where to test

Three walk-in labs

Related packages

Round out the picture

Medically reviewed by Dr Samantha Naidoo, MB ChB, FCP (SA), Medical Director at Epicentre Walk-In Labs. Reviewed 2 June 2026. Epicentre Aids Risk Management (Pty) Ltd provides diagnostic laboratory testing and does not provide diagnoses, treatment or prescriptions to the public; results are intended to inform discussions with a registered healthcare practitioner.

A quick, confidential STI check

No doctor's referral and no fasting needed, with a confidential result in 2 to 5 working days. Book a slot, walk in, or message us with any questions.